IntestInal PermeabilIty

• N-acetyl glucosamine supports GAG synthesis essential for basement membrane structure, with clinical evidence showing 3-6g daily improves IBD symptoms and intestinal permeability recovery

• L-glutamine normalizes intestinal hyperpermeability in IBS and IBD patients while supporting tight junction integrity through claudin protein regulation

• Amino acid complex provides 25-50% of intestinal protein turnover needs, supporting epithelial cell proliferation, repair, and protective mucin synthesis

• Glutamine normalizes intestinal hyperpermeability in IBS and IBD patients while supporting tight junction protein expression

• Zinc carnosine shows superior mucosal healing properties with targeted delivery to sites of intestinal inflammation

• Vitamin D3 regulates critical tight junction genes and epithelial cell restitution for optimal barrier function

• Contains zinc carnosine with superior mucosal adhesion properties for targeted intestinal repair and tight junction protein restoration

• Features clinically-researched anti-inflammatory botanicals that help modulate TNF-alpha and other inflammatory pathways that damage gut barrier integrity

• Includes vitamin D3 to support tight junction protein expression and epithelial cell restoration, addressing a key nutritional deficiency linked to increased intestinal permeability

• Contains Lactobacillus plantarum 299V, a strain related to clinically proven probiotics that reduce intestinal permeability

• Targets pro-inflammatory cytokines like TNF-alpha that damage gut barrier integrity

• Supports tight junction proteins essential for maintaining selective gut permeability