Glycaemic RegulAtIon

• Berberine matched metformin's effectiveness, reducing HbA1c from 9.5% to 7.5% and post-meal glucose from 19.8 to 11.1 mmol/L in clinical trials

• Enhances insulin secretion exclusively during high blood sugar states, providing targeted glucose control with low hypoglycemia risk

• Protects and regenerates pancreatic beta-cells while blocking potassium channels to stimulate natural insulin production

• Chromium picolinate significantly reduces fasting blood glucose levels, with studies showing drops from 8.8 to 7.1 mmol/L over 4 months

• Cinnamon extract lowers HbA1c by 0.83% in 90 days while enhancing insulin sensitivity through PI3k/Akt pathways

• Alpha lipoic acid increases glucose uptake into muscle cells by 300% even in severe insulin resistance cases

• Chromium picolinate significantly reduces both fasting and post-meal blood glucose levels, with clinical studies showing reductions from 8.8 to 7.1 mmol/L in fasting glucose

• Berberine demonstrates equivalent efficacy to pharmaceutical Metformin, reducing HbA1c from 9.5% to 7.5% in newly diagnosed type 2 diabetes

• Silymarin enhances berberine absorption by up to 90% through P-glycoprotein inhibition, maximising therapeutic benefits for glucose metabolism