Elevated EstrOgen

• Supports liver glucuronidation pathways for efficient estrogen elimination from the body

• Clinical studies show 23% reduction in serum estradiol and 55% reduction in estrone levels with increased intake

• Helps prevent reactivation of estrogen metabolites that contribute to hyperestrogenism symptoms

• Increases beneficial 2-OH estrogen detoxification by 66% over problematic 16-OH pathways in just 4 weeks

• Reduces estrogen receptor activation by suppressing ERα gene expression throughout the body

• Supports management of estrogen-dominant conditions like endometriosis, fibroids, and breast tenderness

• Supports healthy estrogen metabolism through B-vitamins that optimize COMT enzyme function, particularly important for the 50-80% of people with genetic COMT mutations

• Contains soy extract with 87% binding affinity for protective ERβ receptors while blocking proliferative ERα effects, clinically shown to improve estrogen detoxification ratios

• Features turmeric and rosemary extracts that enhance liver detoxification pathways and provide anti-proliferative effects against estrogen-sensitive tissue growth

• Inhibits aromatase enzyme activity to reduce testosterone conversion to estrogen in men

• Addresses erectile dysfunction linked to elevated estradiol levels in 20% of affected men

• Helps prevent gynecomastia, which affects up to 70% of men aged 50-69 with high estrogen