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test
Menopause Profile
ANALYTES
Analytes are the substances measured in this test, which include:
DHEAs
Estrone, E1
Estradiol, E2
Progesterone
Testosterone
rESULTS
sample Req.
Hormone levels are interpreted against reference ranges to determine whether concentrations fall within expected limits or demonstrate levels consistent with Peri or Post Menopause in need of intervention.
Low DHEA can indicate later-stage menopause and reduced overall hormonal resilience and often correlates with greater fatigue, lower stress tolerance, and reduced libido, helping gauge systemic aging and endocrine decline beyond ovarian hormones alone.
Estrone E1 declines with ovarian function. Markedly low E1 alongside low E2 is consistent with established or late menopause. The lower the total estrogen pool, the more likely symptoms such as vaginal atrophy, bone loss, and skin thinning become pronounced.
Estradiol E2 is the most sensitive marker of ovarian decline. In early perimenopause, levels fluctuate widely. As menopause progresses, E2 becomes consistently low. Persistently low estradiol reflects more advanced ovarian insufficiency and correlates with increased severity of vasomotor symptoms, sleep disturbance, cognitive decline, genitourinary atrophy, and accelerated bone loss.
Persistently minimal or negligible progesterone levels support confirmation of postmenopause and may contribute to symptoms such as sleep disturbance, heightened anxiety, and reduced stress resilience due to the loss of progesterone’s calming effects.
Low testosterone in mid-to-late menopause can contribute to persistent low energy or sexual dysfunction even when estrogen is addressed. Significant testosterone decline can reflect more advanced endocrine aging.
Saliva
cOST
The results of your health assessment have identified specific signs and symptoms that are clinically consistent with an increased risk of
Peri or Post Menopause
Peri or Post Menopause is associated with a range of signs and symptoms, which have been clinically verified to include
Hot flushes
Sleep disturbances
Accelerated skin aging
Abdominal weight gain
Cognitive impairment
Irritability or low mood
Compromised bone health
Vaginal dryness
Vaginal itching, burning, and irritation
Painful intercourse
Urinary urgency, frequency, incontinence
Recurrent urinary tract infections
Decreased libido
This investigation is optional and may be used to verify the need for therapeutic intervention for Peri or Post Menopause
For optimal interpretive accuracy, for those menstruating we recommend that salivary collection be performed approximately seven days post-ovulation, or in between ovulation and your anticipated next cycle. For precision ovulatory urine sticks are available from the chemist to know exactly when you ovulate.
If menstrual cycle tracking is not feasible, continue with testing.
In the absence of testing, treatment is tailored to address suspected contributors based on the presence of specific signs and symptoms and their degree of correlation with those contributors. If testing is undertaken, the assessment will be re-evaluated in accordance with the test results. You will be updated with the test results alongside any treatment revisions necessary.
A salivary collection kit will be provided for the assessment of midnight cortisol and melatonin levels. The kit includes detailed instructions outlining the required collection protocol to ensure accurate timing and sample integrity.
A pre-addressed, secure return package is included to facilitate safe transport of the specimen to the laboratory, where quantitative analysis will be performed using validated analytical techniques.
Estimated turnaround time: 5 business days
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