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Microscope Close-Up

test

Immune Imbalance Profile

ANALYTES

Analytes are the substances measured in this test, which include:


Proinflammatory Cytokines


  • Interleukin 1

  • Interleukin 6

  • Interleukin 7

  • Interleukin 8

  • Interleukin 17 

  • TNFa

  • TNFb


Anti-inflammatory Cytokines


  • GM-CSF 

  • Interleukin 2

  • Interleukin 4

  • Interleukin 5

  • Interleukin 10

  • Interleukin 12

  • Interleukin 13

  • INFg

Please note these are the same analytes for Muskuloskeletal Inflammation

rESULTS

sample Req.

Regulatory T cells, Tregs, are essential for autoimmune management because they maintain immune tolerance by suppressing autoreactive immune responses, and when their stability or IL-2 support is compromised, immune dysregulation and tissue damage occur.


Interleukins that support Tregs


  • IL-2, critical for Treg survival, proliferation, and suppressive function

  • IL-10, anti-inflammatory cytokine that supports Treg activity


  • IL-6, destabilises FOXP3 expression and can shift immune balance toward pro-inflammatory

  • TNF-α, impairs Treg suppressive capacity and functional stability

  • IL-1, promotes inflammatory signalling that reduce Treg effectiveness


These cytokine concentrations are interpreted in relation to reference ranges to determine whether levels fall within limits consistent with regulatory T cell support and immune balance, or whether they demonstrate a pro-inflammatory profile that impairs Treg stability and function, thereby contributing to autoimmune symptoms and progression.

Blood

cOST

$380

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The results of your health assessment have identified specific signs and symptoms that are clinically consistent with an increased risk of


  • Tregs Dysfunction 


Tregs Dysfunction is associated with a range of signs and symptoms, which have been clinically verified to include


Autoimmune conditions, including:


  • Psoriasis

  • Rheumatoid Arthritis

  • Coeliac Disease

  • Hashimoto’s Thyroiditis

  • Vitiligo

  • Type 1 Diabetes

  • Graves Disease

  • Alopecia Areata

  • Multiple Sclerosis

  • Ankylosing Spondylitis

  • Ulcerative Colitis

  • Crohn’s Disease

  • Systemic Lupus Erythematosus

  • Sjogren's Syndrome

  • Autoimmune Gastritis


Additional Signs:


  • Recurrent Herpes outbreaks

This investigation is optional and may be used to verify the need for therapeutic intervention for Tregs Dysfunction.


In the absence of testing, treatment is tailored to address suspected contributors based on the presence of specific signs and symptoms and their degree of correlation with those contributors. If testing is undertaken, the assessment will be re-evaluated in accordance with the test results. You will be updated with the test results alongside any treatment revisions necessary.

A blood collection kit will be dispatched to you by post.


This collection kit must be presented to an affiliated pathology provider, where a qualified phlebotomist will perform the blood draw and arrange return of the specimen to the laboratory in accordance with standard handling protocols.


Affiliated pathology providers vary by Australian state. Please refer to the list below to identify the appropriate provider for your location:


  • VIC: Melbourne Pathology

  • NSW: 4Cyte Pathology

  • QLD: 4Cyte Pathology

  • SA: Abbott Pathology

  • WA: Western Diagnostic Pathology

  • NT: Western Diagnostic Pathology

  • TAS: TML Pathology

  • ACT: 4Cyte Pathology


Estimated Turnaround Time: 15 business days

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