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test
Advanced DHT
ANALYTES
Analytes are the substances measured in this test, which include:
DiHydroxyTestosterone - DHT
5α-Androstanediol
Androsterone
Etiocholanolone
Please note further analytes in this test are used for both:
Hyperestrogenism
Progesterone Deficiency
Hyperandrogenism
Heavy Metals
If you have been indicated with these, this test provides comprehensive coverage for their evaluation.
rESULTS
sample Req.
Unlike many circulating hormones, DHT is not primarily produced in the bloodstream and then transported to tissues in its active form. Instead, testosterone circulates systemically and, upon entering target tissues such as the skin, scalp, prostate, and sebaceous glands, may be locally converted into DHT through activation of the 5-alpha reductase enzyme. This means that DHT activity is largely determined at the tissue level rather than by the amount freely circulating in blood or excreted in urine.
Additionally, DHT is rapidly metabolised once formed, so systemic measurements may underestimate true androgenic activity within tissues. For this reason, evaluating DHT together with downstream 5-alpha reduced metabolites provides a more reliable indication of DHT levels than DHT in isolation.
These analytes are interpreted in relation to laboratory reference ranges to determine whether levels fall within limits consistent with elevated DHT
DHT, the primary active androgen produced via 5-alpha reductase.
5α-Androstanediol, a downstream metabolite of DHT. Elevated levels reflect increased DHT turnover and sustained 5-alpha reductase pathway activation.
Androsterone, a 5-alpha reduced metabolite of DHT and testosterone. Serves as a functional marker of 5-alpha reductase activity.
Etiocholanolone, a 5-beta reduced androgen metabolite. Acts as a comparative marker to androsterone. The androsterone : etiocholanolone ratio is clinically useful in determining preferential 5-alpha metabolism.
Dried Urine
cOST
The results of your health assessment have identified specific signs and symptoms that are clinically consistent with an increased risk of
Elevated DHT
Elevated DHT is associated with a range of signs and symptoms, which have been clinically verified to include
Male hair loss: recession at the temples and thinning at the crown
Female hair loss: progressive hair thinning in the frontal area of the scalp, particularly along the part line
Oily Skin + Clogged Pores
Acne, particularly lower facial region
This investigation is optional and may be used to verify the need for therapeutic intervention for specific anti-inflammatory support for Elevated DHT
In the absence of testing, treatment is tailored to address suspected contributors based on the presence of specific signs and symptoms and their degree of correlation with those contributors. If testing is undertaken, the assessment will be re-evaluated in accordance with the test results. You will be updated with the test results alongside any treatment revisions necessary.
A dried urinary collection kit will be provided for the assessment of neurotransmitter levels. The kit includes detailed instructions outlining the required collection protocol.
A pre-addressed, secure return package is included to facilitate safe transport of the specimen to the laboratory, where quantitative analysis will be performed using validated analytical techniques.
Estimated Turnaround Time: 10 business days
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