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R0187

Lactobacillus delbrueckii R0187

  • Alleviates Functional Dyspepsia

  • Alleviates Reflux + Heartburn, GORD

  • Alleviates Gastritis + Peptic Ulcers


The product prescribed with Lactobacillus delbrueckii R0187 is combined with soy proteins in order to produce bioactive, anti-inflammatory postbiotic peptides that act as postbiotic that improves reflux and heartburn primarily through anti-inflammatory and mucosal-protective pathways. 


The fermentation produces bioactive peptides and metabolites that suppress key esophageal and gastric inflammatory cytokines, including IL-4, IL-6, and IL-8, thereby reducing mucosal irritation and hypersensitivity to acid exposure. 


FSB also enhances protective prostaglandin E2 activity, strengthening the stomach and esophageal lining. These postbiotic compounds improve epithelial barrier integrity, reduce esophageal sensitivity, promote healthier microbial activity, and support improved gastric emptying, which collectively decrease reflux events and burning sensations over time.

ClInical Results

Dyspepsia Symptoms


Clinical Research has demonstrated after 12 weeks of supplementation with Lactobacillus delbrueckii R0187


  • Heartburn severity reduced by 47.6%

  • Regurgitation episodes by 62.9%

  • Dyspepsia symptoms by 40.9% 

  • Inflammatory cytokine from 20 - 43% [29]

Supplement

Supplements containing R0187

References

 

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6704184/

[2] https://pubmed.ncbi.nlm.nih.gov/21983070/

[3] https://au.sfihealth.com/wp-content/uploads/2025/01/THER_WellMood_RO_APRIL24_v2-1.pdf

[4].https://www.sciencedirect.com/science/article/abs/pii/S0016508517355579

[5] https://pubmed.ncbi.nlm.nih.gov/29380647/

[6] https://pubmed.ncbi.nlm.nih.gov/31413153/

[7] https://pmc.ncbi.nlm.nih.gov/articles/PMC5658588/

[8] https://pmc.ncbi.nlm.nih.gov/articles/PMC10165082/

[9] https://pubmed.ncbi.nlm.nih.gov/14626627/

[10] https://pmc.ncbi.nlm.nih.gov/articles/PMC8306447/

[11] https://www.metagenicsinstitute.com.au/tech-data/lactobacillus-plantarum-299v

[12] https://www.metagenicsinstitute.com.au/tech-data/high-strength-researched-probiotic

[13].https://designsforhealth.com.au/wp-content/uploads/DFH_Saccharomyces-Boulardii_White-Paper_NEW_v1-1.pdf

[14].https://journals.lww.com/jcge/fulltext/2014/11001/can_lactobacillus_fermentum_lf10_and_lactobacillus.27.aspx

[15] https://brill.com/view/journals/bm/10/5/article-p483_1.xml

[16] https://pmc.ncbi.nlm.nih.gov/articles/PMC5592098/

[17] https://pmc.ncbi.nlm.nih.gov/articles/PMC4406132/

[18] https://pmc.ncbi.nlm.nih.gov/articles/PMC7770962/

[19] https://pmc.ncbi.nlm.nih.gov/articles/PMC8850513/

[20] https://pmc.ncbi.nlm.nih.gov/articles/PMC6494655/

[21].https://www.metagenicsinstitute.com.au/tech-data/Lactobacillus-rhamnosus-GR-1-and-Lactobacillus-reuteri-RC-14-liquorice-womens-urogenital-health

[22] https://www.researchgate.net/publication/330572707_

[23] https://www.metagenicsinstitute.com.au/tech-data/lp33-lgg-immune-control

[24].https://assets.contentstack.io/v3/assets/bltaf9269dac47f331a/blt77e65e5bd4cea986/66bc64647cb3ffcecd23bb61/Saccharomyces_boulardii.pdf

[25] https://link.springer.com/article/10.1186/s13223-024-00922-7

[26].https://www.researchgate.net/publication/312202040

[27] https://pmc.ncbi.nlm.nih.gov/articles/PMC6949908/

[28].https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/assessment-of-psychotropiclike-properties-of-a-probiotic-formulation-lactobacillus-helveticus-r0052-and-bifidobacterium-longum-r0175-in-rats-and-human-subjects/2BD9977C6DB7EA40FC9FFA1933C024EA

[29] https://www.mdpi.com/2072-6643/16/16/2779

[30] https://pmc.ncbi.nlm.nih.gov/articles/PMC8110190/

[31].https://academic.oup.com/femspd/article/55/3/324/496928

[32] https://pmc.ncbi.nlm.nih.gov/articles/PMC4733292/

  • Activated Therapeutics, Pepti-BIOTIC

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