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Protozoa seen under a microscope. high resolution image..jpg

MTCC 5260

Bacillus Coagulans MTCC 5260

  • Alleviates abdominal Discomfort + Pain

  • Alleviates Urgent Bowel Motions


Bacillus coagulans MTCC 5260 improve IBS symptoms through several synergistic mechanisms, including modulation of the gut microbiota, enhancement of intestinal motility, and reduction of visceral hypersensitivity. 


As a spore-forming probiotic, it survives gastric acidity and germinates in the small intestine, where it competes with pathogenic organisms, helps restore microbial balance, and supports normal fermentation patterns. This shift in microbial activity improves stool form and helps regulate bowel transit. Additionally, by stabilising the gut environment and reducing luminal triggers associated with pain signalling, the strain decreases sensory nerve activation that contributes to abdominal pain and urgency.

ClInical Results

Clinically, these mechanistic effects translated into substantial symptom improvement as follows

 

  • Abdominal pain decreased by 59%

  • Overall IBS symptom severity improved by 60%, including reductions in bloating, urgency, incomplete evacuation, gas, and bowel habit dissatisfaction. [1]

Supplement

Supplements Containing MTCC 5260

References

 

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6704184/

[2] https://pubmed.ncbi.nlm.nih.gov/21983070/

[3] https://au.sfihealth.com/wp-content/uploads/2025/01/THER_WellMood_RO_APRIL24_v2-1.pdf

[4].https://www.sciencedirect.com/science/article/abs/pii/S0016508517355579

[5] https://pubmed.ncbi.nlm.nih.gov/29380647/

[6] https://pubmed.ncbi.nlm.nih.gov/31413153/

[7] https://pmc.ncbi.nlm.nih.gov/articles/PMC5658588/

[8] https://pmc.ncbi.nlm.nih.gov/articles/PMC10165082/

[9] https://pubmed.ncbi.nlm.nih.gov/14626627/

[10] https://pmc.ncbi.nlm.nih.gov/articles/PMC8306447/

[11] https://www.metagenicsinstitute.com.au/tech-data/lactobacillus-plantarum-299v

[12] https://www.metagenicsinstitute.com.au/tech-data/high-strength-researched-probiotic

[13].https://designsforhealth.com.au/wp-content/uploads/DFH_Saccharomyces-Boulardii_White-Paper_NEW_v1-1.pdf

[14].https://journals.lww.com/jcge/fulltext/2014/11001/can_lactobacillus_fermentum_lf10_and_lactobacillus.27.aspx

[15] https://brill.com/view/journals/bm/10/5/article-p483_1.xml

[16] https://pmc.ncbi.nlm.nih.gov/articles/PMC5592098/

[17] https://pmc.ncbi.nlm.nih.gov/articles/PMC4406132/

[18] https://pmc.ncbi.nlm.nih.gov/articles/PMC7770962/

[19] https://pmc.ncbi.nlm.nih.gov/articles/PMC8850513/

[20] https://pmc.ncbi.nlm.nih.gov/articles/PMC6494655/

[21].https://www.metagenicsinstitute.com.au/tech-data/Lactobacillus-rhamnosus-GR-1-and-Lactobacillus-reuteri-RC-14-liquorice-womens-urogenital-health

[22] https://www.researchgate.net/publication/330572707_

[23] https://www.metagenicsinstitute.com.au/tech-data/lp33-lgg-immune-control

[24].https://assets.contentstack.io/v3/assets/bltaf9269dac47f331a/blt77e65e5bd4cea986/66bc64647cb3ffcecd23bb61/Saccharomyces_boulardii.pdf

[25] https://link.springer.com/article/10.1186/s13223-024-00922-7

[26].https://www.researchgate.net/publication/312202040

[27] https://pmc.ncbi.nlm.nih.gov/articles/PMC6949908/

[28].https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/assessment-of-psychotropiclike-properties-of-a-probiotic-formulation-lactobacillus-helveticus-r0052-and-bifidobacterium-longum-r0175-in-rats-and-human-subjects/2BD9977C6DB7EA40FC9FFA1933C024EA

[29] https://www.mdpi.com/2072-6643/16/16/2779

[30] https://pmc.ncbi.nlm.nih.gov/articles/PMC8110190/

[31].https://academic.oup.com/femspd/article/55/3/324/496928

[32] https://pmc.ncbi.nlm.nih.gov/articles/PMC4733292/

  • Designs for Health, Probiospore 

  • Orthoplex White, Gut SynBiotic

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