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B632 + LS01
Bifidobacterium breve B632 + Lactobacillus salivarius LS01
Alleviates Asthma
Bifidobacterium breve B632, used alongside Lactobacillus salivarius LS01, supports asthma improvement primarily by enhancing gut barrier integrity and regulating mucosal immune responses along the gut–lung axis. B632 promotes regulatory T-cell activity, increases IL-10, and supports epithelial barrier function, which reduces allergen translocation and systemic inflammatory signalling implicated in asthma exacerbations. It also influences microbial composition by suppressing dysbiotic species associated with respiratory infections and allergic airway disease.
When paired with LS01, B632 contributes to a synergistic immunomodulatory effect that reduces airway hyper-responsiveness and improves overall immune tolerance without altering eosinophil counts or spirometry outcomes.
ClInical Results
In a 2024 research meta-analysis review, the LS01 + B632 combination produced a marked reduction in asthma exacerbations, with 24/212 patients experiencing flare-ups compared to 67/210 in the placebo group. This represents a clinically meaningful reduction of approximately 64%. [25]
Supplement
Supplements containing B632 + LS01
References
[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6704184/
[2] https://pubmed.ncbi.nlm.nih.gov/21983070/
[3] https://au.sfihealth.com/wp-content/uploads/2025/01/THER_WellMood_RO_APRIL24_v2-1.pdf
[4].https://www.sciencedirect.com/science/article/abs/pii/S0016508517355579
[5] https://pubmed.ncbi.nlm.nih.gov/29380647/
[6] https://pubmed.ncbi.nlm.nih.gov/31413153/
[7] https://pmc.ncbi.nlm.nih.gov/articles/PMC5658588/
[8] https://pmc.ncbi.nlm.nih.gov/articles/PMC10165082/
[9] https://pubmed.ncbi.nlm.nih.gov/14626627/
[10] https://pmc.ncbi.nlm.nih.gov/articles/PMC8306447/
[11] https://www.metagenicsinstitute.com.au/tech-data/lactobacillus-plantarum-299v
[12] https://www.metagenicsinstitute.com.au/tech-data/high-strength-researched-probiotic
[13].https://designsforhealth.com.au/wp-content/uploads/DFH_Saccharomyces-Boulardii_White-Paper_NEW_v1-1.pdf
[14].https://journals.lww.com/jcge/fulltext/2014/11001/can_lactobacillus_fermentum_lf10_and_lactobacillus.27.aspx
[15] https://brill.com/view/journals/bm/10/5/article-p483_1.xml
[16] https://pmc.ncbi.nlm.nih.gov/articles/PMC5592098/
[17] https://pmc.ncbi.nlm.nih.gov/articles/PMC4406132/
[18] https://pmc.ncbi.nlm.nih.gov/articles/PMC7770962/
[19] https://pmc.ncbi.nlm.nih.gov/articles/PMC8850513/
[20] https://pmc.ncbi.nlm.nih.gov/articles/PMC6494655/
[21].https://www.metagenicsinstitute.com.au/tech-data/Lactobacillus-rhamnosus-GR-1-and-Lactobacillus-reuteri-RC-14-liquorice-womens-urogenital-health
[22] https://www.researchgate.net/publication/330572707_
[23] https://www.metagenicsinstitute.com.au/tech-data/lp33-lgg-immune-control
[24].https://assets.contentstack.io/v3/assets/bltaf9269dac47f331a/blt77e65e5bd4cea986/66bc64647cb3ffcecd23bb61/Saccharomyces_boulardii.pdf
[25] https://link.springer.com/article/10.1186/s13223-024-00922-7
[26].https://www.researchgate.net/publication/312202040
[27] https://pmc.ncbi.nlm.nih.gov/articles/PMC6949908/
[28].https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/assessment-of-psychotropiclike-properties-of-a-probiotic-formulation-lactobacillus-helveticus-r0052-and-bifidobacterium-longum-r0175-in-rats-and-human-subjects/2BD9977C6DB7EA40FC9FFA1933C024EA
[29] https://www.mdpi.com/2072-6643/16/16/2779
[30] https://pmc.ncbi.nlm.nih.gov/articles/PMC8110190/
[31].https://academic.oup.com/femspd/article/55/3/324/496928
[32] https://pmc.ncbi.nlm.nih.gov/articles/PMC4733292/
Activated Probiotics, Biome Breathe Probiotic
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