Adenosine

• Adenocard

Green tea contains caffeine. The caffeine in green tea might block the effects of adenosine, which is often used by doctors to do a test called a cardiac stress test. Stop consuming green tea at least 24 hours before a cardiac stress test.

Antibiotics

• Doxycycline

• Ciprofloxacin

• Amoxicillin

• Azithromycin

• Norfloxacin

• Trimethoprim

The body breaks down caffeine to get rid of it. Some antibiotics might decrease how quickly the body breaks down caffeine. Taking these antibiotics along with green tea can increase the risk of side effects including jitteriness, headache, increased heart rate, and other side effects.

Birth control pills

Green tea contains caffeine. The body breaks down caffeine to get rid of it. Birth control pills can decrease how quickly the body breaks down caffeine. This might increase the risk for side effects from caffeine, such as jitteriness, headache, and fast heartbeat.

Bortezomib

• Velcade

Bortezomib is used in certain types of cancers. Green tea might interact with bortezomib and decrease its effects. If you take bortezomib, avoid taking green tea products.

Carbamazepine

Caffeine can decrease the effects of carbamazepine. Since green tea contains caffeine, taking green tea with carbamazepine might decrease the effects of carbamazepine.

Celiprolol

• Celicard

Green tea appears to decrease how much celiprolol is absorbed into the body. This might decrease the effects of celiprolol.

Cimetidine

• Tagamet

Green tea contains caffeine. The body breaks down caffeine to get rid of it. Cimetidine can decrease how quickly the body breaks down caffeine. Taking cimetidine along with green tea might increase the chance of caffeine side effects including jitteriness, headache, fast heartbeat, and others.

Clozapine

• Clozaril

The body breaks down clozapine to get rid of it. The caffeine in green tea seems to decrease how quickly the body breaks down clozapine. Taking green tea along with clozapine can increase the effects and side effects of clozapine.

Dipyridamole

• Persantine

Green tea contains caffeine. The caffeine in green tea might block the effects of dipyridamole. Dipyridamole is often used by doctors to do a test on the heart called a cardiac stress test. Stop drinking green tea at least 24 hours before a cardiac stress test.

Disulfiram

• Antabuse

The body breaks down caffeine to get rid of it. Disulfiram can decrease how quickly the body gets rid of caffeine. Taking green tea along with disulfiram might increase the effects and side effects of caffeine, including jitteriness, hyperactivity, irritability, and others.

Estrogens

• Oral contraceptive pill

• Estradiol

• Conjugated estrogens

• HRT combination products

The body breaks down the caffeine in green tea to get rid of it. Estrogens can decrease how quickly the body breaks down caffeine. Taking estrogen and drinking green tea can increase the risk of caffeine side effects, including jitteriness, headache, fast heartbeat, and others.

Ethosuximide

• Zarontin

Ethosuximide is a drug used to treat seizures. Caffeine in green tea can decrease the effects of ethosuximide. Taking green tea with ethosuximide might decrease the effects of ethosuximide. This might increase the risk of seizures.

Felbamate

• Felbatol

Felbamate is a drug used to treat seizures. The caffeine in green tea might decrease the effects of felbamate and increase the risk of seizures in some people.

Fexofenadine

• Allegra

Green tea might decrease how much fexofenadine the body absorbs. Separate taking this medication from consuming green tea.

Flutamide

• Eulexin

The body breaks down flutamide to get rid of it. The caffeine in green tea might decrease how quickly the body gets rid of flutamide. This could increase the effects and side effects of flutamide.

Fluvoxamine

• Luvox

The body breaks down the caffeine in green tea to get rid of it. Fluvoxamine can decrease how quickly the body breaks down caffeine. Taking fluvoxamine along with green tea might increase the risk of caffeine side effects such as jitteriness, headache, fast heartbeat, and others.

Imatinib

• Gleevec

Imatinib is used to treat certain types of cancer. Green tea appears to reduce how much imatinib gets into the body. This might decrease the effects of imatinib.

Lisinopril

Green tea appears to decrease how much lisinopril is absorbed into the body. This might decrease the effects of lisinopril.

The caffeine in green tea can increase how quickly the body gets rid of lithium. If you take products that contain caffeine and you take lithium, don't stop taking caffeine all at once. Decrease the daily dose of caffeine slowly. Stopping caffeine too quickly can increase the side effects of lithium.

Medications for asthma

• Beta-adrenergic agonists

Green tea contains caffeine. Caffeine can stimulate the heart. Some medications for asthma can also stimulate the heart. Taking caffeine with some medications for asthma might cause too much stimulation and cause heart problems.

Medications for depression

• MAOIs

Green tea contains caffeine. There is some concern that caffeine can interact with certain medications, called MAOIs. If caffeine is taken with these medications, it might increase the risk for serious side effects including fast heartbeat and very high blood pressure. Some common MAOIs include phenelzine, selegiline, and tranylcypromine.

Medications moved by pumps in cells

• Rosuvastatin

• Atorvastatin

• Simvastatin

• Methotrexate

• Fexofenadine

• Levothyroxine

Some medications are moved in and out of cells by pumps. Green tea might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

• Dabigatran

• Cyclosporine

• Fexofenadine

• Loperamide

• Some HIV antiretrovirals

Medications that can harm the liver

• Acetaminophen / Paracetamol

• Methotrexate

• Atorvastatin

• Simvastatin

• Isoniazid

Green tea extracts might harm the liver. Some medications can also harm the liver. Taking green tea extracts along with a medication that can harm the liver might increase the risk of liver damage.

Medications that slow blood clotting

• Heparin

• Rivaroxaban

• Apixaban

• Dabigatran

• Clopidogrel

Green tea might slow blood clotting. Taking green tea along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Nicotine

Stimulant drugs such as nicotine speed up the nervous system. The caffeine in green tea might also speed up the nervous system. Taking green tea along with stimulant drugs might cause serious problems, including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with caffeine.

Nintedanib

• Ofev

Green tea might decrease how much nintedanib is in the body. It's not clear if this is a real concern.

Pentobarbital

• Nembutal

The stimulant effects of the caffeine in green tea can block the sleep-producing effects of pentobarbital.

Phenobarbital

• Luminal

Phenobarbital is a drug used to treat seizures. The caffeine in green tea might decrease the effects of phenobarbital and increase the risk of seizures in some people.

Phenylpropanolamine

Green tea contains caffeine. Caffeine can stimulate the body. Phenylpropanolamine can also stimulate the body. Taking green tea and phenylpropanolamine together might cause too much stimulation and increase heartbeat and blood pressure and cause nervousness.

Phenytoin

Phenytoin is a drug used to treat seizures. The caffeine in green tea can decrease the effects of phenytoin. Taking green tea with phenytoin might decrease the effects of phenytoin and increase the risk of seizures in some people.

Pioglitazone

• Actos

Green tea contains caffeine. Caffeine might increase the amount of pioglitazone that the body absorbs. Taking green tea might increase the effects and adverse effects of pioglitazone.

Riluzole

• Rilutek

Drinking green tea can decrease how quickly the body breaks down riluzole and increase the effects and side effects of riluzole.

Rosuvastatin

Taking green tea extract might change the amount of rosuvastatin in the blood. This might change the effects and side effects of rosuvastatin.

Stimulant drugs

Stimulants, such as amphetamines and cocaine, speed up the nervous system. By speeding up the nervous system, stimulant medications can increase blood pressure and speed up the heartbeat. Green tea contains caffeine. Caffeine can also speed up the nervous system. Taking green tea along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure.

Theophylline

Green tea contains caffeine. Caffeine works similarly to theophylline. Caffeine can also decrease how quickly the body gets rid of theophylline. Taking green tea along with theophylline might increase the effects and side effects of theophylline.

The caffeine in green tea might decrease the effects of valproate.

Verapamil

• Calan, others

Verapamil can decrease how quickly the body gets rid of caffeine. Drinking green tea and taking verapamil can increase the risk of caffeine side effects including jitteriness, headache, and an increased heartbeat.

• Jantoven

• Used for: blood thinning, clot prevention

Green tea contains vitamin K. Vitamin K can reduce the effect of warfarin. But the amount of vitamin K in green tea is very small. So green tea is unlikely to interact with warfarin when used in moderation. Large amounts of green tea, such as 8 cups or more each day, should be avoided.

Diuretics

• Diuretic drugs

Green tea contains caffeine. Caffeine, especially in large amounts, can reduce potassium levels in the body. "Diuretics" can also decrease potassium in the body. Taking large amounts of caffeine along with "Diuretics" might decrease potassium in the body too much.

Sedative medications

• Diazepam

• Alprazolam

• Temazepam

• Zolpidem

• Zopiclone

• Promethazine

Spearmint might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking spearmint with sedative medications might cause breathing problems and/or too much sleepiness.

Peony might increase the amount of clozapine in the body. Taking peony along with clozapine might increase the effects and side effects from clozapine.

Peony might have some of the same effects as estrogen. Taking peony along with estrogen might increase the effects and side effects from estrogen.

Medications changed by the liver

• Caffeine

• Clozapine

• Olanzapine

• Theophylline

• Tizanidine

• Duloxetine

• Ramelteon

Some medications are changed and broken down by the liver. Peony might change how quickly the liver breaks down these medications. If you are taking medications metabolised by the liver, monitor for any changes in how your medication affects you.

• Atorvastatin

• Simvastatin

• Amlodipine

• Diltiazem

• Cyclosporine

• Tacrolimus

• Midazolam

• Alprazolam

• Rivaroxaban

• Some HIV antiretrovirals

Peony might slow blood clotting. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Peony root might decrease the amount of phenytoin in the body. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures.

• Used for: heart failure, atrial fibrillation

Large amounts of licorice can decrease potassium levels in the body. Low potassium levels can increase the side effects of digoxin.

Licorice seems to change hormone levels in the body. Taking licorice along with estrogen might decrease the effects of estrogen.

Medications changed by the liver

• Cytochrome P450 2B6 substrates

Some medications are changed and broken down by the liver. Licorice might change how quickly the liver breaks down these medications. If you are taking medications metabolised by the liver, monitor for any changes in how your medication affects you.

• Omeprazole

• Esomeprazole

• Clopidogrel

• Diazepam

• Escitalopram

• Sertraline

Medications changed by the liver

• Cytochrome P450 2C8 substrates

• Glipizide

• Phenytoin

• Losartan

Medications for high blood pressure

• Amlodipine

• Ramipril

• Perindopril

• Metoprolol

• Losartan

• Hydrochlorothiazide

Licorice might increase blood pressure. Taking licorice might reduce the effects of blood pressure medications. Monitor your blood pressure closely.

Medications for inflammation

• Corticosteroids

Licorice can decrease how quickly the body breaks down corticosteroids. This can increase the effects and side effects of corticosteroids.

Medications moved by pumps in cells

• P-glycoprotein substrates

Some medications are moved in and out of cells by pumps. Licorice might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

Midazolam

• Versed

Licorice might increase how quickly midazolam is broken down by the body. This might decrease the effects of midazolam.

Paclitaxel

• Abraxane

• Onxol

• Taxol

• Used for: various cancers

Licorice might increase how quickly the body breaks down paclitaxel. Taking licorice with paclitaxel might decrease the effects of paclitaxel.

Warfarin is used to slow blood clotting. Licorice might decrease the effects of warfarin. Decreasing the effects of warfarin might increase the risk of clotting. Be sure to have your blood checked regularly. The dose of your warfarin might need to be changed.

Licorice can decrease potassium levels. "Diuretics" can also decrease potassium levels. Taking licorice along with "Diuretics" might make potassium levels drop too low.

Diuretics

• Loop diuretics

Licorice can decrease potassium levels. Loop diuretics can also decrease potassium levels. Taking licorice and loop diuretics together might make potassium levels drop too low.

Medications for diabetes

• Glyburide

• Glipizide

• Insulin

• Sitagliptin

• Empagliflozin

• Semaglutide

• Dapagliflozin

Fenugreek might lower blood sugar levels. Taking fenugreek along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Fenugreek might slow blood clotting. Taking fenugreek along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Metoprolol

Fenugreek might lower blood pressure. Taking fenugreek with metoprolol might cause blood pressure to drop too low.

Fenugreek might decrease levels of phenytoin in the body. Taking fenugreek with phenytoin might reduce the effects of phenytoin.

Sildenafil

Fenugreek might reduce levels of sildenafil in the body. Taking fenugreek with sildenafil might reduce the effects of sildenafil.

Fenugreek might reduce how much theophylline is absorbed by the body. Using fenugreek while taking theophylline might reduce the effects of theophylline.

Warfarin is used to slow blood clotting. Fenugreek might also slow blood clotting. Taking fenugreek along with warfarin might increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin might need to be changed.

Clopidogrel

Clopidogrel can slow blood clotting. Black seed might also slow blood clotting. Taking black seed along with clopidogrel might increase the chances of bruising and bleeding.

Cyclosporine

• Restasis

• Used for: organ transplant, autoimmune conditions

Black seed might decrease levels of cyclosporine in the blood. This might reduce how well cyclosporine is able to work.

Some medications are changed and broken down by the liver. Black seed might change how quickly the liver breaks down these medications. If you are taking medications metabolised by the liver, monitor for any changes in how your medication affects you.

Black seed might lower blood sugar levels. Taking black seed along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Black seed might lower blood pressure. Taking black seed along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.

Medications that decrease the immune system

• Cyclosporine

• Tacrolimus

• Mycophenolate

• Prednisone

• Methotrexate

• Azathioprine

Black seed can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking black seed along with these medications might decrease the effects of these medications.

Medications that increase serotonin levels in the brain

• Serotonergic Drugs

Black seed might increase a brain chemical called serotonin. Some medications also have this effect. Taking black seed along with these medications might increase serotonin too much. This might cause serious side effects including heart problems, seizures, and vomiting.

Black seed might slow blood clotting. Taking black seed along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Phenytoin is used to control some types of seizures. Black seed may increase or decrease levels of phenytoin in the blood. Taking black seed with phenytoin might reduce the effects or increase the risk of having side effects to phenytoin.

Black seed might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking black seed with sedative medications might cause breathing problems and/or too much sleepiness.

Sildenafil

Black seed might reduce levels of sildenafil in the body. Taking black seed with sildenafil might reduce the effects of sildenafil.

Warfarin is used to slow blood clotting. Black seed might increase the effects of warfarin, which could increase the risk of bleeding.

Black seed can decrease potassium levels. "Diuretics" can also decrease potassium levels. Taking black seed along with "Diuretics" might make potassium levels drop too low.

Atorvastatin

Vitamin D might decrease how much atorvastatin the body absorbs. Taking vitamin D with atorvastatin might decrease the effects of atorvastatin.

Calcipotriene

• Dovonex

Taking vitamin D along with calcipotriene might increase the effects and side effects of calcipotriene.

Taking vitamin D along with digoxin might increase the effects and side effects of digoxin. If you are taking digoxin, talk to your doctor before taking vitamin D supplements.

Diltiazem

• Cardizem, others

Vitamin D helps your body absorb calcium. Calcium can affect the heart. Diltiazem can also affect the heart. Taking large amounts of vitamin D along with diltiazem might decrease the effects of diltiazem.

Verapamil

• Calan, others

Vitamin D helps the body absorb calcium. Calcium can affect the heart. Verapamil can also affect the heart. Do not take large amounts of vitamin D if you are taking verapamil.

Diuretics

• Thiazide diuretics

Vitamin D helps the body absorb calcium. Some "Diuretics" increase the amount of calcium in the body. Taking large amounts of vitamin D along with some "Diuretics" might cause too much calcium in the body. This could cause serious side effects, including kidney problems.