
Clinical Benefits
Clinical Benefits
Moringa also known as ‘the miracle tree’ contains powerful compounds like:
Hydrolysed Tannins, including gallic acid, which can stop egg hatching and kill larvae and bind to proteins in parasites, damaging their structures, and disrupting their energy production.
Saponins, which break down worm egg membranes and can paralyze parasites, weakening them until they are expelled from the body.
Flavonoids, such as quercetin, luteolin, caffeic acid, which can disrupt parasite development, damage egg shells, and enhance the immune response.
Terpenoids and alkaloids, which also play a role in parasite control [36],[37].
These compounds work synergistically, becoming more effective together than alone.
Clinical studies have demonstrated Moringa can:
Inhibit up to 99% of helminth egg hatching
Kill larvae at high rates
Damage worm cuticles and internal organs
Prevent egg development by interfering with proteins in the eggshell
Increases immunity specific to Helminth infection, with an increase in CD4+ T cell numbers [36],[37]
Clinically effective against:
Roundworm - Ascaris lumbricoides
Roundworm - Strongyloides spp.
Whipworm - Trichuris trichiura.
Hookworm - Anctlostoma duodenale
Tapeworm - Hymenolepis spp
A study tested how effective the equivalent of no more than a ¼ of a teaspoon of Moringa leaf extract added to water alone when consumed caused the killing of eggs from three types of helminths. The killing efficiency was as follows:
Ascaris x 96%
Trichuris x 99.5%
Ankylostoma x 98.9% [38]
A study testing the anti-hemetic effect of drinking 10mL of Moringa leaf juice against Roundworm (Ascaris) eggs showed Moringa leaf juice reduced egg counts by 54% after 2 days and 98% by day 4, which was clinically as effective as Mebendazole [39]
A study using Moringa leaf supplements showed a dose dependent efficiency against Roundworm - Strongyloides spp [40].
A study on Moringa Extract against the Tapeworm - Hymenolepis spp demonstrated fewer adult worms and eggs, as well as improvements in gut health, including better villi structure, increases in beneficial immune responses (Th2-type) and higher levels of supportive IgA antibodies [41].
Ingredients
Moringa oleifera (leaf)
Instructions
Instructions
Dosage
2 heaped teaspoons (7.5 g) in water, smoothie or juice
Duration
4 weeks
Warnings
Always read the label
Dietary supplements should not replace a balanced diet
If symptoms persist, worsen or change unexpectedly, consult your healthcare professional
Contraindications
Contraindications
This supplement may interact with the following categories of medications, as well as specific active ingredients.
• Medications changed by the liver - refer list
• Medications moved by pumps in cells - refer list
• Medications for diabetes
• Nevirapine
Further details are provided below.
Please note that medications may be sold under different brand names, so check the listed active ingredients against your medication packaging.
Major Interactions
Moderate Interactions
Medications changed by the liver
• Atorvastatin
• Simvastatin
• Amlodipine
• Diltiazem
• Cyclosporine
• Tacrolimus
• Midazolam
• Alprazolam
• Rivaroxaban
• Some HIV antiretrovirals
Some medications are changed and broken down by the liver. Moringa might change how quickly the liver breaks down these medications. If you are taking medications metabolised by the liver, monitor for any changes in how your medication affects you.
Medications moved by pumps in cells
• P-glycoprotein substrates
Some medications are moved in and out of cells by pumps. Moringa might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Minor Interactions
Medications changed by the liver
• Caffeine
• Clozapine
• Olanzapine
• Theophylline
• Tizanidine
• Duloxetine
• Ramelteon
Some medications are changed and broken down by the liver. Moringa might change how quickly the liver breaks down these medications. If you are taking medications metabolised by the liver, monitor for any changes in how your medication affects you.
Medications for diabetes
• Metformin
• Glyburide
• Glipizide
• Insulin
• Sitagliptin
• Empagliflozin
• Semaglutide
• Dapagliflozin
Moringa might lower blood sugar levels. Taking moringa along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Nevirapine
• Viramune
Moringa might decrease how quickly the liver breaks nevirapine. This might increase the effects and side effects of nevirapine. But it's not clear if this is a real concern.
