Clinical Benefits
Clinical Benefits
The Clivers Complex provides targeted herbal support for lymphatic congestion, a condition where impaired lymph flow and poor clearance of harmful substances can manifest as skin issues, swelling, recurrent infections, and chronic inflammation. The lymphatic system's network of vessels and nodes plays a crucial role in immune surveillance, fluid balance, and toxin removal throughout the body.
Cleavers (Galium aparine) serves as the cornerstone ingredient, offering powerful immunostimulatory effects that directly address lymphatic dysfunction. Clinical research demonstrates that cleavers extract significantly enhances lymphocyte proliferation by 7-8 times the normal amount [39],[40]. This dramatic increase in immune cell production improves lymphatic detoxification and supports healthy lymph node function, making it particularly beneficial for existing infections affecting the lymphatics, such as those manifesting in skin eruptions or rashes.
Sarsaparilla (Smilax ornata) and Oregon grape (Berberis aquifolium) provide complementary support through their traditional use in supporting lymphatic drainage and skin health. These herbs work synergistically to enhance the body's natural detoxification processes and support clear, healthy skin by addressing underlying lymphatic congestion that can contribute to various dermatological conditions.
Burdock (Arctium lappa) and Yellow dock (Rumex crispus) complete this comprehensive formula by supporting the body's natural cleansing pathways. These traditional lymphatic herbs help facilitate the removal of metabolic waste and support healthy liver function, which works closely with the lymphatic system in processing toxins and maintaining overall systemic health.
While not specifically detailed in clinical lymphatic research, these botanicals are well-recognized in traditional herbal medicine for their ability to support natural detoxification processes and promote healthy skin through improved elimination pathways. Together, this synergistic blend addresses multiple aspects of lymphatic health to support optimal immune function and clear, vibrant skin.
Ingredients
Galium aparine (Cleavers) ext.
720 μL 360 mg
ext. equiv. dry (herb)
720 μL 360 mg
Smilax ornata (Sarsaparilla) ext.
720 μL 360 mg
ext. equiv. dry (root & rhizome)
540 μL 270 mg
Berberis aquifolium (Oregon grape) ext.
ext. equiv. dry (root & rhizome)
Arctium lappa (Burdock) ext.
ext. equiv. dry (root)
Rumex crispus (Yellow dock) ext.
ext. equiv. dry (root)
540 μL 270 mg
Instructions
Instructions
Dosage
2 tablets 2 times daily
Duration
Minimum duration of 4 weeks, with continuation guided by symptom response
Suitable for long-term lymphatic support
Warnings
Do not use if pregnant or likely to become pregnant
Always read the label
Dietary supplements should not replace a balanced diet
If symptoms persist, worsen or change unexpectedly, consult your healthcare professional
Contraindications
Contraindications
This supplement may interact with the following categories of medications, as well as specific active ingredients.
• Medications changed by the liver - refer list
• Medications for diabetes
• Medications for high blood pressure
• Medications moved by pumps in cells - refer list
• Medications that slow blood clotting
• Sedative medications
• Diuretics
• Warfarin
Further details are provided below.
Please note that medications may be sold under different brand names, so check the listed active ingredients against your medication packaging.
Major Interactions
Diuretics
• Diuretic drugs
Yellow dock is a laxative. Some laxatives can cause diarrhea and decrease potassium levels. "Diuretics" can also decrease potassium levels. Taking yellow dock along with "Diuretics" might make potassium levels drop too low.
Moderate Interactions
Medications changed by the liver
• Glipizide
• Phenytoin
• Losartan
Some medications are changed and broken down by the liver. Oregon grape might change how quickly the liver breaks down these medications. If you are taking medications metabolised by the liver, monitor for any changes in how your medication affects you.
• Tramadol
• Metoprolol
• Fluoxetine
• Paroxetine
• Tamoxifen
• Amitriptyline
• Atorvastatin
• Simvastatin
• Amlodipine
• Diltiazem
• Cyclosporine
• Tacrolimus
• Midazolam
• Alprazolam
• Rivaroxaban
• Some HIV antiretrovirals
Medications for diabetes
• Glyburide
• Glipizide
• Insulin
• Sitagliptin
• Empagliflozin
• Semaglutide
• Dapagliflozin
Oregon grape might lower blood sugar levels. Taking Oregon grape along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Medications for high blood pressure
• Amlodipine
• Ramipril
• Perindopril
• Metoprolol
• Losartan
• Hydrochlorothiazide
Oregon grape might lower blood pressure. Taking Oregon grape along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.
Medications moved by pumps in cells
• P-glycoprotein substrates
Some medications are moved in and out of cells by pumps. Oregon grape might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Medications that slow blood clotting
• Heparin
• Rivaroxaban
• Apixaban
• Dabigatran
• Clopidogrel
Oregon grape might slow blood clotting. Taking Oregon grape along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Sedative medications
• Diazepam
• Alprazolam
• Temazepam
• Zolpidem
• Zopiclone
• Promethazine
Oregon grape might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking Oregon grape with sedative medications might cause breathing problems and/or too much sleepiness.
• Jantoven
• Used for: blood thinning, clot prevention
Yellow dock can work as a laxative and cause diarrhea. Diarrhea can increase the effects of warfarin and increase the risk of bleeding.
Sarsaparilla might have an effect like a water pill or "diuretic. " Taking sarsaparilla might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects.
Minor Interactions
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• Increases lymphocyte proliferation by 7-8 times to dramatically improve lymphatic detoxification and immune function
• Particularly effective for skin eruptions and rashes caused by lymphatic infections and congestion
• Supports healthy lymph node function to enhance the body's natural ability to clear toxins and waste products